6 Thesis layout

BACKGROUND
- Research question
- Report style and philosophy
- Ethics and Reproducibility
  - Science for the profit of whom?
  - Importance of reproducibility
  - Ethics and reproducibility go together
- Data Hazards
- Memory and Learning
  - Why study CaMKII and NMDAR interactions to study memory formation?
  - A brief history background on learning and memory research
  - Long Term Potentiation
  - NMDA receptors structure and functions
  - CaMKII structure and functions
  - Bringing it all together: LTP, CaMKII/NMDAR complex as a molecular memory and interactions within the postsynaptic neuron
- Why use computational modelling to study biological systems?
  - How do we model biochemical systems networks?
  - Rule Based Modelling
  - BioNetGen
  - MCell
  - Biodynamo
METHODS
- Model Description
- Model development and validation
  - A reproducible model
RESULTS